近日,来自西安交通大学的研究者们在Int J Biol Sci.杂志上发表了题为“VEGFA/NRP-1/GAPVD1 axis promotes progression and cancer stemness of triple-negative breast cancer by enhancing tumor cell-macrophage crosstalk”的文章,该研究提示VEGFA诱导的TNBC细胞与tam之间存在串扰,为免疫治疗与VEGFA靶向药物联合治疗TNBC提供了潜在的意义。
Lu Wang et al. VEGFA/NRP-1/GAPVD1 axis promotes progression and cancer stemness of triple-negative breast cancer by enhancing tumor cell-macrophage crosstalk. Int J Biol Sci. 2024 Jan 1;20(2):446-463. doi: 10.7150/ijbs.86085.