The companies will partner to advance KRAS inhibitorKRAS inhibitor candidates through IND-enabling studies. Credit: Alexander Raths / Shutterstock.com.
The companies will partner to advance the KRAS inhibitorKRAS inhibitor candidates through IND-enabling studies.
Jazz will subsequently oversee their clinical development, regulatory processes, production and marketing.
The candidates include molecules selective for G12D mutations and pan-KRAS inhibitors.
Jazz will also compensate Redx for conducting research and preclinical development activities.
Jazz Pharmaceuticals research and development global head and executive vice-president Robert Iannone stated: “KRAS is a well-validated oncology target and there remains a high unmet need for innovation in this area based on challenges in developing molecules to target specific KRAS mutations.
“Redx has discovered a number of preclinical KRAS candidates and we plan to leverage our collective oncology development expertise to identify and advance the most promising molecules toward the clinic.
“This transaction further expands our early-stage oncology pipeline, and we are excited to explore novel approaches to improving treatment options for cancer patients.”