近日,来自美国堪萨斯大学的研究者们在Acta Pharm Sin B.杂志上发表了题为“High-throughput screening of novel TFEB agonists in protecting against acetaminophen-induced liver injury in mice”的文章,该研究表明基因和药理激活TFEB可能是预防AILI的一种很有前途的方法。
Xiaojuan Chao et al. High-throughput screening of novel TFEB agonists in protecting against acetaminophen-induced liver injury in mice. Acta Pharm Sin B. 2024 Jan;14(1):190-206. doi: 10.1016/j.apsb.2023.10.017.