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项与 Desvenlafaxine Benzoate 相关的临床试验 / Not yet recruitingN/AIIT Comparing the Efficacy and Safety of Pregabalin Monotherapy With Pregabalin Combined Other Neuromodulatory Drugs (Desvenlafaxine) in the Treatment of Fibromyalgia: A Multicenter Clinical Study
Fibromyalgia (FM) is a chronic pain syndrome characterized by widespread pain, fatigue, and emotional disorders. Its onset is related to factors such as central sensitization and imbalance of neurotransmitters. The current mainstream treatments include pregabalin, but the efficacy of pregabalin is limited, with only 25%-40% pain relief rate, and adverse reactions are common. Selective serotonin and norepinephrine reuptake inhibitors (SNRIs), such as duloxetine and venlafaxine, have demonstrated efficacy in FM by modulating pain pathways through increased serotonin and norepinephrine availability. Desvenlafaxine, the third SNRI, was found with lower adverse effects compared with duloxetine and venlafaxine. We hypothesize that the combination of pregabalin with desvenlafaxine may offer greater pain relief compared pregabalin monotherapy, without a significant increase in adverse effects for patients with FM.
/ Not yet recruiting临床1期IIT A Multiple-dose, Randomized, Open-label, Crossover Bioequivalence Study of Generic Desvenlafaxine 50 mg Extended-release Tablets and Reference Product (Pristiq) in Healthy Thai Volunteers under Fasting Conditions
A Single-dose, Randomized, Open-label, Crossover Bioequivalence Study of Generic Desvenlafaxine 50 mg Extended-release Tablets and Reference Product in Healthy Thai Volunteers under Fasting and Fed Conditions
100 项与 Desvenlafaxine Benzoate 相关的临床结果
100 项与 Desvenlafaxine Benzoate 相关的转化医学
100 项与 Desvenlafaxine Benzoate 相关的专利(医药)
100 项与 Desvenlafaxine Benzoate 相关的药物交易