预约演示
更新于：2025-04-12
Apocyanin
香草乙酮
更新于：2025-04-12
概要
基本信息
结构/序列
分子式C9H10O3 |
InChIKeyDFYRUELUNQRZTB-UHFFFAOYSA-N |
CAS号498-02-2 |
关联
8
项与 香草乙酮 相关的临床试验CTIS2023-508791-11-00
A placebo-controlled, double-blinded, randomized, dose-finding trial using a combination of apocynin and paeonol (APPA) for the treatment of knee osteoarthritis
EUCTR2020-000249-14-DK
A placebo-controlled, double-blinded, randomized, trial using a combination of apocynin and paeonol (APPA) for the treatment of knee osteoarthritis
IRCT20200418047122N1
Evaluation of the protective effect of a combination drug including Apocynin, Niacin, and Tannin on prevention of cardiovascular and respiratory morbidities and mortality in COVID-19 infection: A Clinical Trial
100 项与 香草乙酮 相关的临床结果
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100 项与 香草乙酮 相关的转化医学
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100 项与 香草乙酮 相关的专利（医药）
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6,425
项与 香草乙酮 相关的文献（医药）2025-06-01SEPARATION AND PURIFICATION TECHNOLOGY
Catalytic oxidative depolymerization of lignin to aromatic compounds using transition metal doped ionic Liquid-based polyoxometalate catalysts
作者: Shi, Junyou ; Zhao, Luyao ; Zhang, Yu ; Deng, Haoyu ; Xu, Wenbiao ; Li, Mingfei
Significant attention has been focused on the depolymerization of lignin into monophenolics, as lignin is the most abundant biomass feedstock, and its valorization is considered crucial for a complete biomass refinery.In this study, we investigate catalytic oxidative depolymerization using novel bimetallic transition metal (Ni and Co) doped ionic liquid-polyoxometalate (ILPOM) composites under aerobic conditions.We systematically evaluate various catalysts, including [MIMPS]H2PW12O40, Ni[MIMPS]PW12O40, Co[MIMPS]PW12O40, [MIMPS]H2PMo12O40, Ni[MIMPS]PMo12O40, and Co[MIMPS]PMo12O40, assessing their impact on monomer yield and selectivity.Notably, Co[MIMPS]PMo12O40 emerges as a superior catalyst, producing high yields of key aromatic monomers, primarily vanillin and Me vanillate, under optimized conditions.Addnl., the Co[MIMPS]PMo12O40 catalyst demonstrates effective cleavage of the C-O and/or Cα-Cβ bonds within a β-O-4 dimer model compound, indicating potential catalytic cracking capabilities.This investigation elucidates the intricate interplay among transition metals, ionic liquids (ILs), and lignin, providing a novel pathway for lignin transformation.
2025-05-01FUEL
The integrated process of CO2 reforming of methane with co-pyrolysis of Naomaohu coal and elm to improve tar yield
作者: Jin, Lijun ; Dai, Zhenghua ; Zhong, Mei ; Luo, Jie ; Liu, Yang
Co-pyrolysis of coal and biomass is an effective route to replace coal utilization with alternative biomass resource.However, it is crucial to acquire high tar yield during co-pyrolysis.To improve tar yield during co-pyrolysis of Naomaohu coal and elm, in this work, a new process was constructed by integrating co-pyrolysis with CO2 reforming of methane over 10Ni/γ-Al2O3 catalyst (CP-CRM) on an IR-heated fixed-bed reactor, and the effect of pyrolysis temperatures on the integrated process was investigated.The comparison of co-pyrolysis behaviors under N2 (CP-N2) or CH4/CO2 (CP-CH4/CO2) atm. was conducted to reveal the reaction mechanism during CP-CRM.Result revealed that the CP-CRM showed higher tar yield than co-pyrolysis under CP-N2, and the maximum tar yield of 21.68 wt% was achieved at 500 °C during the integrated process, which was 1.13 times as that under CP-N2.In comparison, tar yield in co-pyrolysis under CH4/CO2 mixture gas was between those of CP-N2 and CP-CRM, indicating that CH4 and CO2 themselves could facilitate the formation of tar, which could further be strengthened under the action of 10Ni/γ-Al2O3 catalyst.The analyses of co-pyrolysis tar by simulated distillation, GC/MS, 1H-NMR and 13C-NMR showed that the pitch content in co-pyrolysis tar from CP-CRM was higher than those in CH4/CO2 and N2 atmospheres, and high phenols content up to 60.05 % was obtained, higher than 51.61 % in tar from CP-N2.Addnl., the tar from CP-CRM possessed more aromatics with short side chains compared than those from pyrolysis under N2 and CH4/CO2, which was mainly ascribed to the participation of active free radicals from CO2 reforming of CH4.This work provides a simple route to improve tar yield and phenols content in tar during co-pyrolysis.
2025-04-01FOOD CHEMISTRY
Non-targeted analysis using gas chromatography mass spectrometry to assess the free and bound aroma fingerprints of the emblematic Greek white winegrape varieties and guarantee varietal authenticity using multivariate chemometrics
Article
作者: Gkrimpizis, Theodoros ; Kalogiouri, Natasa P ; Ouroumi, Niki-Athina ; Karadimou, Christina ; Chatzidimitriou, Effimia ; Menkissoglu-Spiroudi, Urania ; Theocharis, Serafeim ; Koundouras, Stefanos
A non-targeted analytical approach using gas chromatography-mass spectrometry (GC-MS) is proposed for the analysis of the free and bound volatile fractions of three emblematic indigenous Greek white winegrape varieties belonging to Vidiano, Malagousia, and Savvatiano and establish volatile varietal markers using multivariate chemometrics. A total of 89 free and 103 bound volatile compounds were identified, categorized into alcohols, aldehydes, esters, acids, terpenes, norisoprenoids, C6 compounds, phenols, and ketones. A robust Partial Least Squares Discriminant Analysis (PLS-DA) prediction model was developed and validated, and successfully classified the grape samples according to the variety with 100 % accuracy, demonstrating the potential of volatile profiling as a non-targeted fingerprinting approach for varietal discrimination. Malagousia variety exhibited the highest concentration of terpenes, particularly in the bound fraction, highlighting its intense floral character. The proposed analytical workflow was successfully applied for the investigation of the unique aroma profiles of Greek white winegrape varieties. The findings contribute to the understanding of unique volatile fingerprints of the winegrape varieties and support the adaptation of vineyard and winery practices to enhance their varietal expression.
100 项与 香草乙酮 相关的药物交易
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研发状态
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| 适应症 | 最高研发状态 | 国家/地区 | 公司 | 日期 |
|---|---|---|---|---|
| 动脉粥样硬化 | 临床1期 | - | - | - |
| 糖尿病性神经病变 | 临床1期 | - | - | - |
| 高血压 | 临床1期 | - | - | - |
| 炎症性肠病 | 临床1期 | - | - | - |
| 帕金森病 | 临床1期 | - | - | - |
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临床结果
临床结果
适应症
分期
评价
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N/A | - | - | 膚積醖製襯醖鬱壓餘獵(簾鑰糧憲餘製積鏇簾壓) = 積遞醖憲觸積構壓願夢 醖艱積遞築艱網窪夢齋 (觸醖艱鹹構齋齋夢夢糧 ) | 积极 | 2024-06-05 | ||
築選鹹夢夢齋顧簾齋廠(廠鏇衊糧鹹鑰遞淵願艱) = 膚鹽遞構鹽廠糧艱遞鏇 鏇艱網範蓋繭繭鏇鏇憲 (夢鑰艱觸簾構窪糧憲鏇 ) 更多 | |||||||
N/A | - | Apocynin and paeonol (APPA) | 鬱壓齋鑰鏇壓醖憲廠顧(衊衊齋憲積願齋衊廠鹽) = 窪膚窪壓範廠構艱顧窪 願簾窪齋選憲窪壓網襯 (鑰觸願齋淵廠網淵窪觸 ) | 积极 | 2020-06-03 | ||
N/A | - | - | AN-1 | 淵範夢衊衊積夢遞夢積(鏇網選艱範築製構鹽廠) = 齋齋獵鬱齋齋鹽製憲餘 憲襯淵繭鑰鑰襯衊鏇衊 (遞淵製顧淵廠艱簾餘願 ) 更多 | - | 2013-07-30 | |
淵範夢衊衊積夢遞夢積(鏇網選艱範築製構鹽廠) = 蓋膚獵夢憲壓築齋鏇網 憲襯淵繭鑰鑰襯衊鏇衊 (遞淵製顧淵廠艱簾餘願 ) 更多 | |||||||
N/A | 高血压 reactive oxygen species (ROS) | - | 鏇蓋願繭選顧鏇繭糧艱(襯願壓顧觸積壓觸憲壓) = 醖製構鬱鹽餘構齋鏇餘 壓鏇觸鏇糧積淵願簾願 (餘繭遞網廠構遞窪廠繭 ) 更多 | 积极 | 2012-09-01 | ||
鏇蓋願繭選顧鏇繭糧艱(襯願壓顧觸積壓觸憲壓) = 艱醖衊範糧積築廠淵齋 壓鏇觸鏇糧積淵願簾願 (餘繭遞網廠構遞窪廠繭 ) | |||||||
N/A | - | - | 鏇繭憲構網鏇鹹構廠顧(夢製範鹽淵製簾夢獵獵) = 顧鏇齋衊壓醖齋顧襯繭 觸醖窪醖醖窪淵膚憲蓋 (顧選衊獵艱窪範繭襯艱 ) 更多 | - | 2011-09-01 | ||
N/A | 14 | 網廠糧觸遞蓋壓艱遞窪(餘鏇膚遞鬱遞膚窪鑰夢) = 餘壓範鏇構憲膚蓋糧襯 艱糧蓋範鏇範壓壓網製 (憲繭願鏇遞顧製築積夢 ) 更多 | 积极 | 2011-09-01 | |||
Placebo | 網廠糧觸遞蓋壓艱遞窪(餘鏇膚遞鬱遞膚窪鑰夢) = 簾壓選鹹艱築鏇願壓遞 艱糧蓋範鏇範壓壓網製 (憲繭願鏇遞顧製築積夢 ) 更多 | ||||||
N/A | - | - | 鹽窪鹽壓蓋鹽艱蓋範鹹(醖膚窪夢蓋獵醖憲鏇顧) = 夢壓繭鏇鏇鹹齋遞衊壓 衊鑰願醖壓築積網醖鏇 (憲衊觸餘築壓艱衊選鹹 ) 更多 | - | 2011-09-01 | ||
Placebo | 鹽窪鹽壓蓋鹽艱蓋範鹹(醖膚窪夢蓋獵醖憲鏇顧) = 繭觸齋糧醖淵積遞積顧 衊鑰願醖壓築積網醖鏇 (憲衊觸餘築壓艱衊選鹹 ) 更多 |
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