Comparative evaluation of Cefdinir and Amoxicillin with Clavulanic acid in cases of Acute otitis media in adult population- A randomized control trial - NIL

开始日期2024-08-30

申办/合作机构-

DRKS00033456 / RecruitingN/AIIT

Antibiotic consumption, course of therapy and costs in primary care of GP, pediatric and ENT practices - HaHNOPAKT

开始日期2024-05-21

申办/合作机构-

IRCT20240108060650N1 / Recruiting临床3期IIT

Investigating the effectiveness of intratympanic corticosteroid treatment in comparison with standard treatment on hearing condition in adults with serous otitis

开始日期2023-10-23

申办/合作机构

Shahid Beheshti University of Medical Sciences

100 项与急性渗出性中耳炎相关的临床结果

登录后查看更多信息

100 项与急性渗出性中耳炎相关的转化医学

登录后查看更多信息

0 项与急性渗出性中耳炎相关的专利（医药）

登录后查看更多信息

523

项与急性渗出性中耳炎相关的文献（医药）

2024-10-01·Anales de Pediatría (English Edition)

Use of topical antibiotic therapy in acute otitis media with otorrhea: Results of a national survey

Article

作者: Marín Córdoba, Carlota ; Molina Gutiérrez, Miguel Ángel ; de Ceano-Vivas, María ; Garcia de Oteyza, Maria

2024-09-27·Medicine

Causal relationship between allergic rhinitis and otitis media: A Mendelian randomization study

Article

作者: Yu, Chenyang ; Wang, Fule ; Liu, Rongkui

Otitis media and allergic rhinitis are prevalent conditions. Some data posit a significant association between the 2 ailments, proposing mechanisms such as allergic rhinitis-induced Eustachian tube dysfunction or concurrent allergic pathophysiology affecting both the nasal and aural cavities. Observational studies hint at an association between allergic rhinitis (AR) and nonsuppurative otitis media, yet definitive causality remains elusive. Thus, to elucidate the causal impact of AR on otitis media, a 2-sample Mendelian randomization study was undertaken. Data on AR, acute suppurative otitis media, chronic suppurative otitis media, and nonsuppurative otitis media were sourced from the Genome for Extensive Association Study, encompassing individuals of European ancestry. Single nucleotide polymorphisms linked with AR were utilized as instrumental variables. The inverse-variance weighting (IVW) method, alongside sensitivity analyses employing the weighted median and Mendelian randomization-Egger methods, was employed to assess causal effects. Our analysis revealed a significant causal effect of AR on nonsuppurative otitis media (IVW, odds ratio [OR] = 12.22, 95% confidence interval, 1.38–107.93, P = .024) and indicated an association with acute suppurative otitis media (IVW, OR = 6.95, 95% confidence interval, 0.80–60.35, P = .078). However, no causal effect of AR on chronic suppurative otitis media was discerned. Our findings delineate a measurable causal link between AR and nonsuppurative otitis media (OR = 12.22) and suggest an association with acute suppurative otitis media (OR = 6.95), though lacking evidence for a causal effect on chronic suppurative otitis media. These results underscore the propensity of AR to correlate with diverse forms of otitis media and furnish high-quality causal evidence pertinent to clinical management.

2024-09-01·Ear, Nose & Throat Journal

Facial Paralysis in Otitis Media Due to Granulomatosis with Polyangiitis

Article

作者: Yazdani, Yalda ; Djalilian, Hamid R. ; Chao, Madeleine C.

Granulomatosis with polyangiitis (GPA), formerly Wegener’s granulomatosis, commonly presents primarily with otitis media and hearing loss, as well as upper and lower respiratory symptoms. However, facial nerve paralysis is a rare manifestation of this uncommon necrotizing vasculitis. We report a patient with facial paralysis accompanied by otitis media. In further studies, our patient was diagnosed with GPA, which was neglected before. In such a presentation, acute suppurative otitis media is the most likely cause of the facial paralysis, but GPA must also be considered, especially in cases with new-onset, painful serous otitis, acute otitis media, or pale granulation tissue in the middle ear, in adults with no previous history of Eustachian tube dysfunction.