The accuracy of the instrument is good, and the results of blind detection using APGC Xevo TQ-S are consistent with the comparative results of blind and blind constant The instrument has good reproducibility, and after continuous 10-needle (n = 10) injection, the relative standard deviation %RSD of 17 kinds of dioxins calculated by use of isotopes is <5%. The instrument sensitivity is good, and taking 2,3,7,8-TCDD as an example, resp. 20 fg is injected and calculated to obtain S/N=205 (P/P raw data, 20 fg). The standard curve of the detection method is good, and the linear curve of dioxins (17 kinds) is R>0.999 (diluting the GC-HRMS standard curve by 10 times/500 times resp.).