In the pesticide production process, a large number of volatile organic waste VOCs can be produced, they can irritate the human respiratory tract, eyes, and some are carcinogenic, and are related to PM2.5 and haze weather, so much attention has been paid to the management of the volatile organic compounds Regenerative thermal oxidizer is the most commonly used for volatile organic exhaust gas disposal of pesticide industry. In this article, from the aspects of waste gas characteristics in the pesticide industry, the working principle of regenerative thermal oxidizer (RTO), process design, equipment selection, waste gas collection, safety design, etc., the design points of RTO were briefly described.