A review. Recently "Scavenger silica gels" have been applied in industrial fields especially for pharmaceutical and elec. devices to remove heavy metals which remaining in the organic products used as catalyst metals. It is important for the safety of human health to remove trace metals in pharmaceutical products. "Scavenger silica gels", that have appropriate organic groups introduced on the surface of silica gel. are applied for this purpose. We introduce the synthesis and application of the scavenger silica gels in this review. Catalytic synthesis of the scavenger silica gels and an application to removal of cesium ion are also reviewed.