BOZEMAN, MT and VANCOUVER, BC, Nov. 3, 2022 /PRNewswire/ - Microbion Corporation today announced that the company will present a poster at the North American Cystic Fibrosis Conference, November 3 – 5, in Philadelphia, PA highlighting the activity of pravibismane against bacterial pathogens associated with lung infection in people with cystic fibrosis (CF). The objective of this study was to measure the minimal inhibitory concentration of pravibismane on pathogens commonly associated with CF lung infections and to determine whether the presence of pulmonary surfactant impacted pravibismane's activity. Pravibismane's activity was compared to a panel of frontline antibiotics clinically used to manage these infections. Financial support for this study was provided by CARB-X. Date and Time: November 3, 2022, from 12:00 p.m. – 1:00 p.m. ET; and November 4, 2022, from 12:00 p.m. – 12:40 p.m. ET
Presenting Author: Dr. Brett Baker, President and Chief Innovation Officer, Microbion Online abstract link: click here
Pravibismane was found to be generally more potent, as measured by MIC90, than commonly used first- or second-line agents in susceptible and resistant bacterial species such as Pseudomonas aeruginosa, Staphylococcus aureus, Acinetobacter baumannii, Stenotrophomonas maltophilia, Burkholderia cepacia complex, and Mycobacterium abscessus. The presence of pulmonary surfactant did not have an impact on pravibismane activity. Disclaimer: Research reported in this press release is supported by the Cooperative Agreement Number IDSEP160030 from ASPR/BARDA and by awards from Wellcome Trust and Germany's Federal Ministry of Education and Research, as administrated by CARB-X. The content is solely the responsibility of the authors and does not necessarily represent the official views of the Department of Health and Human Services Office of the Assistant Secretary for Preparedness and Response, CARB-X, or other funders. For more information visit: www.microbioncorp.com.
Certain of the statements made in this press release are forward-looking, such as those, among others, relating to the success of clinical development of pravibismane and preparation for potential commercialization. These statements are subject to risks and uncertainties that could cause actual results and events to differ materially from those anticipated, including, but not limited to, risks and uncertainties related to: our ability to enroll patients in our clinical trials at the pace that we project; the size and growth of the potential markets for pravibismane or any future product candidates and our ability to serve those markets; our ability to obtain and maintain regulatory approval of pravibismane or any future product candidates; and our expectations regarding the potential safety, efficacy or clinical utility of pravibismane or any future product candidates. Actual results or developments may differ materially from those projected or implied in these forward-looking statements. Microbion Corporation disclaims any intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise.