Just Drinking 3 Cups of Coffee a Day Could Help Slash the Risk of Diabetes and Obesity

2023-03-20

临床结果

Drinking three to five cups of coffee every day is linked with a lower risk of developing obesity or type 2 diabetes, according to a recent study published in the journal BMJ Medicine . Of note, this generally adds to the many health benefits associated with caffeine and is useful to those trying to tackle gaining weight and developing type 2 diabetes . Evidence from prior studies shows that, compared with non-coffee drinkers, those who drink up to three to five cups of coffee a day have a lowered risk of developing type 2 diabetes and cardiovascular diseases. (function(v,d,o,ai){ai=d.createElement("script");ai.defer=true;ai.async=true;ai.src=v.location.protocol+o;d.head.appendChild(ai);})(window, document, "//a.vdo.ai/core/v-druggenius/vdo.ai.js"); window.vdo_ai_ = window.vdo_ai_ || {}; window.vdo_ai_.dimensions = window.vdo_ai_.dimensions || []; vdo_ai_.dimensions.push( [ "v-druggenius", "dim1", "/news/just-drinking-3-cups-of-coffee-a-day-could-help-slash-the-risk-of-diabetes-and-obesity/" ] ); vdo_ai_.dimensions.push( [ "v-druggenius", "dim2", "439155" ] ); vdo_ai_.dimensions.push( [ "v-druggenius", "dim3", "" ] ); vdo_ai_.dimensions.push( [ "v-druggenius", "dim4", "organic" ] ); This is the first study to analyze the effect of caffeine on the risk of type 2 diabetes and the onset of cardiovascular disease. Scientists in Sweden made use of the technique called Mendelian randomization to determine the effects of prolonged exposure to higher blood caffeine concentrations on body fat, type 2 diabetes, and major cardiovascular diseases. People who carry genetic variants that are tied to slower caffeine metabolism drink, on average, less coffee. However, this group of people tends to also have high concentrations of caffeine in their blood. For this study, researchers obtained data from over 10,000 participants of European ancestry from a total of six population-based studies. They used Mendelian randomization to identify the two common genetic variants that are responsible for how fast or slowly the body metabolizes caffeine: CYP1A2 and AHR. The team also collected genetic data for type 2 diabetes and cardiovascular diseases from the individuals that participated in the six cohorts. There, they found that those who were genetically prone to having higher concentrations of caffeine in the blood were more likely to have a lower body mass index (BMI) and lower body fat. In the same way, they were also likely to have a lower risk of type 2 diabetes. On the other hand, they found no strong link between genetically predicted caffeine levels in the blood and the risk of heart-related disease outcomes. The researchers point out that about half (43 percent) of the effect of caffeine on type 2 diabetes is likely driven by the decrease in body weight . They further explain that caffeine reduces body fat by increasing the breakdown of fat and increasing energy expenditure. For instance, taking 100 mg of caffeine every day (the equivalent of one cup of coffee) has been shown to raise energy expenditure by roughly 100 calories per day, which could eventually reduce the risk of obesity. “Randomized controlled trials are warranted to assess whether non-caloric caffeine-containing beverages might play a role in reducing the risk of obesity and type 2 diabetes,” the authors write in the paper. While it’s easy to resort to increasing your coffee intake, keep in mind that consuming too much could have potential negative effects on the body. Ideally, sticking to moderate amounts is key. All in all, findings from this study bring forth strong evidence to support the link between increased blood concentrations of caffeine with low body fat and the risk of type 2 diabetes.

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机构

BMJ Medical Management, Inc.

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