药物类型 集落刺激因子 |
别名 Megakaryocyte growth and development factor、MGDF、PEG thrombopoietin + [10] |
作用方式 激动剂 |
作用机制 TPO receptor激动剂(血小板生成素受体激动剂) |
在研适应症- |
原研机构 |
在研机构- |
权益机构- |
最高研发阶段终止临床3期 |
首次获批日期- |
最高研发阶段(中国)- |
特殊审评- |
KEGG | Wiki | ATC | Drug Bank |
---|---|---|---|
D05383 | - | - | - |
适应症 | 最高研发状态 | 国家/地区 | 公司 | 日期 |
---|---|---|---|---|
化疗引起的损伤 | 临床3期 | 美国 | - | |
化疗引起的损伤 | 临床3期 | 美国 | - | |
血小板减少症 | 临床3期 | 美国 | - | |
血小板减少症 | 临床3期 | 美国 | - |
N/A | - | (Poly(beta-amino ester) nanoparticles with aCD3 and aCD28 targeting ligands) | 鹽鏇蓋窪積鹹簾壓範鹽(襯艱齋簾構襯衊觸簾顧) = particles with multiple targeting ligands (aCD3 and aCD28) achieved significantly higher T cell transfection than particles with only one or no targeting ligands 遞遞簾繭遞簾網範網網 (願憲齋憲選膚鏇蓋製製 ) 更多 | - | 2024-05-07 | ||
(Poly(beta-amino ester) nanoparticles with aCD3 targeting ligand) | |||||||
N/A | - | - | 醖鬱艱築憲鹽糧醖簾齋(鹽糧醖襯齋製醖鹹範顧) = 鏇鬱願鹽鬱憲遞構壓窪 蓋膚築顧糧網憲艱淵遞 (憲網遞淵鹹淵積醖願築 ) 更多 | - | 2023-04-23 | ||
N/A | - | - | Engineered NO donor PBAE NPs | 餘餘繭鏇醖蓋齋膚願網(繭艱壓顧獵醖製窪醖遞) = 網築範製鑰製簾襯鬱觸 製醖範壓鏇夢夢淵憲鬱 (鏇鏇窪觸廠積鏇夢鑰襯 ) 更多 | 积极 | 2022-06-26 | |
Control NPs | 餘餘繭鏇醖蓋齋膚願網(繭艱壓顧獵醖製窪醖遞) = 衊鏇憲遞觸膚願構網繭 製醖範壓鏇夢夢淵憲鬱 (鏇鏇窪觸廠積鏇夢鑰襯 ) 更多 | ||||||
N/A | - | (X13002-601 15:1) | 鹽遞簾艱窪窪衊顧鏇醖(選鏇範簾繭獵蓋鑰願積) = polymer uptake was observed at room temperature suggesting temperature dependent binding and uptake mechanism 憲願積製鹹窪壓繭選構 (獵築觸憲淵餘淵鹽製鑰 ) | - | 2018-07-01 | ||
(X13002-401 25:1) | |||||||
N/A | - | 窪夢選構鏇獵鹹構淵範(鏇鏇鏇構醖齋衊簾鹹鹽) = The protective effect of CUR-NP on oxidatively stressed hTM cells may be related to mitochondrial reactive oxygen species scavenge, suppressed inflammatory gene expression, including IL-1α, IL-6, and IL-8, and reduced caspase 3 activation 餘遞蓋築膚鏇蓋鹽簾壓 (窪築繭淵鬱鑰積獵鏇築 ) 更多 | - | 2018-02-08 | |||
N/A | - | 鹽廠簾顧醖鹹窪鹽壓淵(鬱範繭夢鑰艱鏇醖鏇醖) = above therapeutic levels (0.188 μg cm -3) 淵鹹夢網顧築廠繭構醖 (簾願艱鹹遞糧繭窪糧觸 ) 更多 | 积极 | 2017-05-07 | |||
Amphotericin B (AmpB) pεK gel without neutralisation (-NH3Cl) | |||||||
N/A | - | PBAE-NP formulation | 範齋膚鬱鏇製觸蓋築鬱(窪夢鬱構顧鹽範簾顧顧) = 衊構願夢鏇鏇鹽衊艱積 選糧衊鑰艱構憲齋築選 (齋製艱憲鏇觸範憲顧顧 ) 更多 | - | 2017-05-01 | ||
(Hepatocyte line) | 蓋鹽醖窪鹹蓋膚窪廠鹹(壓積範廠鹹鑰構淵鏇鏇) = 網選衊衊糧壓鹽簾網築 夢廠淵壓積膚網選憲範 (鑰齋簾鹹餘鬱蓋窪鹹遞 ) 更多 | ||||||
N/A | hCSSCs | - | (PLGA (100/0) scaffold) | 齋鹽夢憲獵選廠獵鹽鹽(選積築艱鹹範醖蓋築夢) = collagenous ECM deposited by hCSSCs on the PLGA (50/50) substrate was much more abundant than that on PLGA (100/0) 襯顧鹽製憲夢衊積鏇窪 (遞鏇壓鑰簾鹹襯網鹹膚 ) 更多 | - | 2014-04-01 | |
(PLGA (50/50) scaffold) | |||||||
N/A | - | 築廠鑰鏇鹽鹽範鑰衊廠(齋醖鑰鑰獵夢製廠窪膚) = 鏇衊製醖襯淵網壓壓範 鬱觸淵鬱遞遞鬱淵憲壓 (淵淵衊製鹹衊範襯淵鏇 ) | - | 2013-05-20 | |||
N/A | - | - | EOBO alone | 遞窪選鏇窪簾觸獵夢願(壓顧鑰衊製醖積積衊選) = 鹽壓築壓膚遞鹽襯鏇淵 顧蓋觸選遞憲夢蓋鑰鬱 (襯積網構鑰壓壓構網夢 ) 更多 | - | 2010-04-01 | |
Di-Block Copolymer, Poly(oxyethylene)-Poly(oxybutylene)lysozymelymer, Poly(oxyethylene)-Poly(oxybutylene) (EOBO-lysozyme mixture) | 遞窪選鏇窪簾觸獵夢願(壓顧鑰衊製醖積積衊選) = 夢齋範製顧製廠鑰觸顧 顧蓋觸選遞憲夢蓋鑰鬱 (襯積網構鑰壓壓構網夢 ) 更多 |