漆树提取物(Sumac Extract) - _专利_临床

概要

基本信息

药物类型

中药

别名

Rhus、Somagh

靶点-

作用机制-

治疗领域

其他疾病

在研适应症-

非在研适应症

高尿酸血症体重增加

原研机构

Shiraz University of Medical Sciences

在研机构-

非在研机构

Shiraz University of Medical Sciences

最高研发阶段无进展临床阶段不明

首次获批日期-

最高研发阶段(中国)-

特殊审评-

关联

2

项与漆树提取物相关的临床试验

NCT02891031 / Unknown statusN/AIIT

The Effects of Rhus Coriaria L. on Serum Uric Acid Levels

The aim of this study is to evaluate the effects of Rhus coriaria L. (Rhus) commonly known as "Somagh" on serum uric acid levels.

开始日期2019-06-01

申办/合作机构

Shiraz University of Medical Sciences

NCT02754089 / CompletedN/AIIT

The Effects of Rhus Coriaria L. (Rhus or Somagh) on Body Weight

The aim of this study is to evaluate the effects of Rhus coriaria L. (Rhus) commonly known as "Somagh" on body weight.

开始日期2016-05-01

申办/合作机构

Shiraz University of Medical Sciences

100 项与漆树提取物相关的临床结果

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100 项与漆树提取物相关的转化医学

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100 项与漆树提取物相关的专利（医药）

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143

项与漆树提取物相关的文献（医药）

2024-11-01·International Journal of Biological Macromolecules

Application of bacterial nanocellulose film loaded with sodium nitrite, sumac, and black carrot extracts to reduce sodium nitrite, extend shelf life, and inhibit Clostridium perfringens in cooked beef ham

Article

作者: Shiravani, Zolaikha ; Aliakbarlu, Javad ; Moradi, Mehran

This study aimed to develop innovative bacterial nanocellulose (BNC) films incorporated with sodium nitrite (SN), sumac extract (SE), and black carrot extract (BCE) to reduce sodium nitrite, extend shelf life, and inhibit Clostridium perfringens in cooked beef ham. The ham covered with BNC film immersed in SE (10 % w/v) + BCE (5 % w/v) + SN (125 ppm) (SE₁₀BCE₅SN₁₂₅) exhibited the lowest microbial load (4.39, 4.32, 3.83, and 4.6 log cycles reductions in total viable count, lactic acid bacteria, Enterobacteriaceae, and C. perfringens, respectively) and the lowest oxidation rate (70 % reduction compared to control) on day 28 of storage. The samples covered with SE₁₀BCE₅SN₁₂₅ film had also the lowest level of residual nitrite (64 % lower compered to positive control). Positive control (ham containing 120 ppm SN) and ham covered with SE₁₀BCE₅SN₁₂₅ film had the highest redness. It was concluded that the films developed in this study have the potential to reduce the use of sodium nitrite in beef ham production.

2024-10-01·Prostaglandins & Other Lipid Mediators

The effect of sumac on cardiovascular risk factors in adults: A systematic review and meta-analysis of randomized controlled trials

Review

作者: Pourteymour Fard Tabrizi, Fatemeh ; Khajeh, Mahsa ; Hojati, Ali ; Abbasalizad-Farhangi, Mahdieh ; Gataa, Ibrahim Saeed ; Noshadi, Nooshin ; Vajdi, Mahdi ; Nikrad, Negin ; Darzi, Melika ; Alipour, Beitullah

Clinical evidence suggests the beneficial effects of sumac on cardiovascular risk factors. However, these results are controversial. This systematic review and meta-analysis of randomized controlled trials (RCTs) was performed to determine the effect of sumac supplementation on cardiovascular risk factors in adults. The PubMed, Embase, Web of Science, and Cochrane databases were searched from inception to 30 December 2023 to identify RCTs that were published in English. Data were presented as weighted mean difference (WMD) and associated 95 % confidence interval (CI). The quality of the included trials was measured using the Cochrane Collaboration's modified risk of bias tool. A pooled analysis of 16 trials showed that sumac consumption led to a significant reduction in fasting blood glucose (WMD: -6.03 mg/dl; 95 % CI: -9.67 to -2.39), hemoglobin A1c (WMD: -0.45 %; 95 % CI: -0.59 to -0.31), triglycerides (WMD: -9.07 mg/dL; 95 % CI: -16.19 to -1.94), low-density lipoprotein cholesterol (WMD: -5.58 mg/dL; 95 % CI: -11.27 to -0.12), BMI (WMD: -0.22 kg/m²; 95 % CI: -0.38 to -0.05), weight (WMD: -0.85 kg; 95 % CI: -1.44 to -0.27), waist circumference (WMD: -0.54 cm; 95 % CI: -0.92 to -0.15), and diastolic blood pressure (WMD: -2.72 mmHg; 95 % CI: -4.16 to -1.29). High-density lipoprotein-cholesterol level also increased significantly (WMD: 3.69 mg/dL; 95 % CI: 1.81-5.57). The overall results support possible protective and therapeutic effects of sumac on cardiovascular risk factors in adults. Additional prospective studies are suggested using longer intervention periods and higher supplementation doses to confirm these results.

2024-10-01·International Dental Journal

Comparison of Two Oral Pastes Containing Triamcinolone and Rhus Coriaria L. for Treating Minor Aphthous Lesions

Article

作者: Mirzadeh, Monirsadat ; Mokhlesi, Aida ; Zarabadipour, Mahdieh ; cheshme soltani, Masoume Tork ; Cheshme Soltani, Masoume Tork ; Rezvani, Zeinab

BACKGROUNDRecurrent aphthous stomatitis (RAS) is a common oral mucosal lesion. Herbal medicine has been explored to treat this condition. This study compared the effectiveness of two oral pastes containing Triamcinolone and Sumac, for the healing, size, and symptomatology of RAS.METHODSThis triple-blind randomized clinical trial included 60 patients with minor aphthous ulcers. Participants were informed about the study and provided consent. Exclusion criteria consisted of specific medical conditions and medication use. The patients were divided into three groups and received either Sumac adhesive gel, Triadent oral paste, or a placebo. Ulcer size was measured before and after treatment. The medication was prepared using carboxymethylcellulose-based gel and Sumac powder extract. The study was triple-blinded, and the groups were labelled as A, B, and C. Data analysis was performed using SPSS version 22, employing repeated measurement, student t test, Kolmogorov-Smirnoff, and one-way ANOVA for quantitative data. Statistical significance was set at P ≤ .05.RESULTSA clinical trial involving 59 participants compared the Sumac, Triadent, and placebo groups. The Sumac group exhibited the shortest healing time, significantly reduced lesion size, and lower Visual Analog Scale scores. Triadent took the longest time to heal ulcers. ANOVA test indicated no significant difference in age and gender distribution.CONCLUSIONThis clinical trial evaluated two oral pastes for treating aphthous ulcers and found that the Sumac group achieved faster healing and reduced lesion size compared to the Triadent and control groups. Sumac shows promise as a treatment option, but further studies are necessary to confirm its efficacy and safety. These favourable results support the use of herbal treatments and suggest their potential for broader utilization in managing diseases such as RAS.

100 项与漆树提取物相关的药物交易

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