1区 · 医学
Article
作者: Rodgers, Buel D. ; Bernardo, Bianca C. ; Loveland, Kate L. ; Liu, Yingying ; Hagg, Adam ; Chen, Justin L. ; Sepulveda, Patricio V. ; Gregorevic, Paul ; Walton, Kelly L. ; McMullen, Julie R. ; Winbanks, Catherine E. ; Lynch, Gordon S. ; Harrison, Craig A. ; Qian, Hongwei ; Murphy, Kate T. ; Thomson, Rachel E. ; Beyer, Claudia
Muscle-directed
Smad7
gene delivery prevents the loss of skeletal muscle mass and strength in mouse models of cachexia, an important contributor to poor prognosis in patients with advanced cancer.