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项与 CD3/CD28-Costimulated Autologous T-Cells(Abramson Cancer Center of the University of Pennsylvania) 相关的临床试验A Phase-I, Dose Escalation Study of Recombinant Human Interleukin-18 (Sb-485232) Combined With Adoptive Transfer of Vaccine-Primed CD3/CD28-Costimulated Autologous T-Cells Following Lymphodepletion for Adult Patients With Recurrent Ovarian, Fallopian Tube or Primary Peritoneal Cancer
This is a phase-I, dose escalation study to assess the safety and biological activity of cyclophosphamide/fludarabine lymphodepletion followed by adoptive transfer of vaccine-primed, ex vivo CD3/CD28-costimulated peripheral blood autologous T-cells, and recombinant human interleukin-18 (SB-485232, IL-18) treatment in adult patients with recurrent, Stage III or IV ovarian cancer, fallopian tube or primary peritoneal cancer who previously underwent induction vaccination with whole tumor vaccine
A Phase-1 Trial of Adoptive Transfer of Vaccine-Primed CD3/CD28-Costimulated Autologous T-Cells Combined With Vaccine Boost and Bevacizumab for Recurrent Ovarian Fallopian Tube or Primary Peritoneal Cancer Previously Vaccinated With Autologous Tumor Vaccine
This is a phase-I clinical trial to determine the feasibility and safety of Cyclophosphamide/Fludarabine Lymphodepletion and an immunomodulatory combination of Interferon-alpha Bevacizumab and Aspirin followed by adoptive transfer of vaccine-primed ex vivo CD3/CD28-costimulated peripheral blood autologous T cells and vaccination with whole tumor vaccine administered intradermally in combination with Bevacizumab in patients with recurrent ovarian cancer fallopian tube or primary peritoneal cancer. (Funding Source - FDA OOPD)
100 项与 CD3/CD28-Costimulated Autologous T-Cells(Abramson Cancer Center of the University of Pennsylvania) 相关的临床结果
100 项与 CD3/CD28-Costimulated Autologous T-Cells(Abramson Cancer Center of the University of Pennsylvania) 相关的转化医学
100 项与 CD3/CD28-Costimulated Autologous T-Cells(Abramson Cancer Center of the University of Pennsylvania) 相关的专利(医药)
100 项与 CD3/CD28-Costimulated Autologous T-Cells(Abramson Cancer Center of the University of Pennsylvania) 相关的药物交易