Background:::Alkaloids are important phytoconstituents obtained from various plant
sources. The study's primary goal is to assess the anti-Alzheimer potential of alkaloids using a molecular
docking study. Alzheimer's disease (AD) is considered a gradual decline in memory, reasoning,
decision-making, orientation to one's physical surroundings, and language.
Method and Material::The main target i.e. acetylcholinesterase proteins was selected for the molecular
docking study.
Result:::The structures of various alkaloids were drawn using Chem Draw Software, PDB was retrieved
from the RCSB PDB database, and molecular docking study was performed on Molergo Virtual
Docker. The potential alkaloids were identified with anti-Alzheimer potency.
Conclusion:::Reserpine, vinblastine, ergotamine, and tubocurarine were found to exhibit potential
anti-Alzheimer potency.