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Concern over the influences of constant addition of anthropogenic chemicals to the marine environment has attracted public attention. Organophosphate esters (OPEs) and phthalate esters (PAEs) were two emerging chemicals frequently added to a variety of products as flame retardants and plasticizers. However, limited information is available associated with their environmental behaviors in marine environment, and the tissue-specific bioaccumulation and biomagnification of OPEs and PAEs in fish remain subjects of ongoing debate. Hence, 12 OPE and 6 PA E analogues were analyzed in five marine fish species from the coast of Wenchang, Hainan province. The concentrations of Σ₁₂OPEs and Σ₆PAEs were in the range of 319-1790 ng/g lw and 400-1370 ng/g lw, respectively. Significantly negative correlations (p value < 0.05) were observed between the concentration of pollutants and their corresponding lipid contents of fish tissues. There were no obvious correlations between the logarithmic transformed concentrations of each OPE and PAE analogue with their corresponding Log K_OW value in fish tissues, but OPE and PAE concentrations were likely to reach the highest when Log K_OW values were around five. Significantly negative correlations (p value < 0.05) were found between logarithmic transformed concentrations of TCEP, TCP and BBP along with δ¹⁵N values in fish species, except for TDCIPP, TEHP and DBP which exhibited an increasing trend with the increasing of δ¹⁵N values. Furthermore, human exposure via fish intakes was assessed, and EDI ranged from 73.9 to 1910 ng/kg bw/day for ∑OPEs and 495-4550 ng/kg bw/day for ∑PAEs, respectively, which were both within the safe dose threshold, and the HI values of ΣOPEs and ΣPAEs were much lower than the boundary value of 1.00. This study contributes valuable insights into OPEs and PAEs present in marine organisms as well as robust evidence indicating that most OPE and PAE analogues undergo trophic dilution within marine fish.