Contezolid acefosamil(Akashi Therapeutics)(Contezolid acefosamil(Akashi Therapeutics))

概要

基本信息

药物类型

小分子化药

别名-

靶点

PLA2

作用机制

PLA2抑制剂(磷脂酶A2抑制剂)

治疗领域

免疫系统疾病感染耳鼻咽喉疾病+ [1]

在研适应症-

非在研适应症

过敏性鼻炎

原研机构

Akashi Therapeutics Inc

在研机构-

非在研机构

Akashi Therapeutics Inc

Celsus Therapeutics Plc

最高研发阶段无进展临床2期

首次获批日期-

最高研发阶段(中国)-

特殊审评-

登录后查看时间轴

关联

2

项与 Contezolid acefosamil(Akashi Therapeutics) 相关的临床试验

NCT03033329 / Completed临床1期

A Randomized, Double-Blind, Placebo Controlled Three-Part Study of the Safety, Tolerability, and Pharmacokinetics of MRX 4 Administered Intravenously to Healthy Volunteers in Single Ascending and Multiple Ascending Dose Cohorts, and Bioavailability of Oral MRX-4 Versus Intravenous Administration

A Phase 1 study of the safety, tolerability, and pharmacokinetics of a new oxazolidinone antibiotic. In Part 1 cohorts of healthy adults will participate in a single dose escalation study of increasing intravenous doses of MRX-4. In Part 2 cohorts of healthy adults will participate in a multiple dose escalation study of increasing intravenous doses of MRX-4 given twice daily for ten days. Part 3 is a crossover study of oral MRX-4 versus a comparable intravenous dose of MRX-4 to determine bioavailability.

开始日期2016-10-01

申办/合作机构

MicuRx Pharmaceuticals, Inc.

[+1]

NCT03033342 / Completed临床1期

Randomized, Double-Blind, Placebo-Controlled Three-Part Phase 1 Study of Safety, Tolerability, Pharmacokinetics, and Food Effect of MRX-4 Administered Orally to Healthy Volunteers in Single and Multiple Ascending Dose Cohorts to Evaluate Drug Interactions With Omeprazole

A phase one study of the safety, tolerability, and pharmacokinetics of a new oxazolidinone antibiotic. Cohorts of healthy adults (female and male) will participate in:
single dose escalation study of increasing doses of MRX-4 given by mouth others will participate in multiple dose escalation cohorts of MRX-4 given twice daily by mouth.
other cohorts of subjects will participate in the study to evaluate the impact of concomitant food or Omeprazole on safety, tolerability and pharmacokinetics of MRX-4

开始日期2016-08-02

申办/合作机构

MicuRx Pharmaceuticals, Inc.

[+1]

100 项与 Contezolid acefosamil(Akashi Therapeutics) 相关的临床结果

登录后查看更多信息

100 项与 Contezolid acefosamil(Akashi Therapeutics) 相关的转化医学

登录后查看更多信息

100 项与 Contezolid acefosamil(Akashi Therapeutics) 相关的专利（医药）

登录后查看更多信息

100 项与 Contezolid acefosamil(Akashi Therapeutics) 相关的药物交易

登录后查看更多信息