更新于:2024-11-01

Paralysis, Hyperkalemic Periodic

高钾性周期性麻痹

基本信息

别名
ADYNAMIA EPISODICA HEREDITARIA、ADYNAMIA EPISODICA HEREDITARIA WITH OR WITHOUT MYOTONIA、Adynamia Episodica Hereditaria
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简介
An autosomal dominant familial disorder which presents in infancy or childhood and is characterized by episodes of weakness associated with hyperkalemia. During attacks, muscles of the lower extremities are initially affected, followed by the lower trunk and arms. Episodes last from 15-60 minutes and typically occur after a period of rest following exercise. A defect in skeletal muscle sodium channels has been identified as the cause of this condition. Normokalemic periodic paralysis is a closely related disorder marked by a lack of alterations in potassium levels during attacks of weakness. (Adams et al., Principles of Neurology, 6th ed, p1481)

分析

对领域进行一次全面的分析。
对领域进行一次全面的分析。
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